Manifestations of Xanax overdose include:
- diminished reflexes,
- impaired coordination,
Moreover, in some cases, deaths have been reported in relation with overdoses. Furthermore, fatalities have also been reported where people overdosed Xanax with alcohol; however levels of alcohol witnessed in some of these people have been lower, when compared to alcohol-induced fatality.
The intense oral LD50 in mice is 331-2172mg/kg. Other tests in animals have pointed that cardiopulmonary collapse could happen following large intravenous xanax doses (more than 195mg/kg; extremely more than the maximum prescribed daily human dosage of 10mg a day). Animals can be revived with intravenous norepinephrine bitartrate and positive mechanical ventilation. Animal trials have indicated that forced hemodialysis or diuresis is likely of little significance in treating over-dosage.
Xanax pills pose such a serious threat of overdose that the effect of this pill occurs very fast after ingesting the drug. Comparing it with other medicines, it is relatively fast acting. It is an addictive drug as the individuals solely rely on it when they get anxious and want to calm down the stressful day. Hence, Xanax use as well as abuse is on the rise in the world. It is more toxic in most of the relatively toxic cases thereby leading to complicated severe cases of overdoses. Since the rates of prescribing are climbing high hence the drug availability also continues to climb. Buy Xanax online overnight from our reliable online drug store and ensure to take it only for the time period specified by the doctor to avoid risk of overdose.
Signs and Symptoms of Xanax Overdose:
It involves difficulty concentrating, drowsiness, joint pain, changes in appetite, constipation, dry mouth, nausea, tiredness, irritability, increased salivation, difficulty passing urine or changes in sex drive. Few among these symptoms are accurate gauge for the likelihood of the progression of overdose, one must monitor about the person feels in the next hours after the onset of the symptoms of overdose. Stay with the person having Xanax overdose and check his breathing and immediately ask for medical assistance. Buy Xanax bars online and get cheap drugs at your doorstep on time.
Treatment of Overdose
Overdose reports with Xanax have actually been limited. As with all cases of overdose, blood pressure, pulse rate and respiration should be monitored. Supportive measures must be taken along with instant gastric lavage. In addition, intravenous fluids must be given and adequate airway maintained. In the case of hypotension, it may be handled and controlled by vasopressors. It must be noted that dialysis has limited value. With management of intentional overdose with any medicine, it should be remembered that multiple agents might have been ingested.
Flumazenil, which is a particular benzodiazepine receptor antagonist, is meant for partial or complete reversal of benzodiazepines’ sedative effects, and may be utilized in situations when a benzodiazepine overdose is suspected or known. Before administering flumazenil, necessary steps should be taken to secure ventilation, airway and intravenous access. People should keep in mind that flumazenil is meant as an ancillary, not as an alternative for management of overdose of benzodiazepine. People treated with this drug must be monitored for respiratory depression and re-sedation.
The treatment of the individuals having anxiety should be started with Xanax dose of 0.25 to 0.5mg to be given three times in a day. The dose might be increased to attain maximum therapeutic effect at the gap of three to four days. It should not reach more than four mg in a day which should be administered in proper dosage. The dependence risk may increase with the dosage and duration of the treatment. Buy Xanax online legally and ensure to treat anxiety under medical supervision.
The dosage must be reduced gradually when you need to discontinue the therapy or when you need to reduce the daily dose.
For the successful treatment of panic disorder the Xanax dosage required is more than 4mg in a day. In controlled trials the mean dosage of Xanax was around 5 to 6 mg every day. Few occasional patients required dosage as much as 10mg in a day to get successful response.
The treatment must be initiated with 0.5mg of Xanax three times every day. After checking the response the dosage may be increased at the intervals of three to four days with the increment of not more than 1mg in a day.